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Benzene Reports
Benzene is most known for its ability to cause chronic forms of
poisoning and injury, especially on the hematopoietic system. Prior
to this knowledge, the use of benzene, particularly as a solvent,
led to the high exposure
of benzene to the workers. The exposure to benzene was regularly
at levels around 500 ppm, with some cases exceeding 1,000 ppm. Currently,
the workplace benzene exposure limits for NIOSH for airborne exposure
limit is 0.1 ppm averaged over a 10-hour work shift and 1 ppm not
to be exceeded during any 15-minute work period.
Review articles as early as 1926 mentioned reports of fatal cases
of benzene poisoning. In 1909, there were three girls in Maryland
that had been exposed to benzene for a period of 4-5 months and
died within 1 month. The girls' exposure to benzene came from vapors
of a commercial grade of benzene that was used as a rubber solvent
in sealing tin cans.
In 1920, chronic benzene poisoning was reported in two men who
had been spreading balloon fabric with rubber. The reports were
made in England by Legge, which provided the firs measurements of
benzene levels in workroom atmospheres for workers exposed on a
chronic basis determined by a chemist. Legge concluded that though
the range of benzene exposure levels were measured to range from
210-800 ppm, the fact that the spreading room contained such poor
ventilation could have made the concentration as high as 16,800
ppm.
Cases of chronic benzene poisoning continued to increase in number
due to the use of benzene beginning to be used in a wide array of
industries. These reports of benzene poisoning also began to appear
in more literature and investigations resulted due to the serious
and deadly effects benzene poisoning was having on those exposed.
As more and more people learned of the dangers of exposure to benzene,
eventually it began to become replaced with other solvents.
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